Yes, that's exactly what I use when purging and leak checking units. I have a bottle of C25 gas that has found a second purpose in life besides mig welding. Works just fine. I pressurize to around 200 psi and let the rig sit for an hour after curing obvious leaks.
Just remember to draw a deep vacuum on your system afterwards. The deeper, the better. Especially if you're using R410a. It and the oil it uses both hate water. In fact, the mfr's recommend replacing the oil if it ever contacts the atmosphere. The oil absorbs water and doesn't let it go, like brake fluid.
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