Style?
Synthetics absorb and wick your sweat, so they pick up body odors quickly.
Polyester t-shirts don't have as much insulation as cotton, but you can cover with a fleece sweater, which is very warm.
For winter conditions, a good system is a wicking base (t-shirt, khaki pants) covered with fleece sweater and pants, and that is covered with a nylon wind or rain pants and jacket.
Another disadvantage is for work clothes, heavy cotton jeans can take more abuse and protect you from abrasion better than synthetics.
Nylon wind pants and coats are sometimes noisy, as you brush your sleeves against the coat for example.
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